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ARVO 2025
Kuria presented a poster at ARVO 2025 in Salt Lake City, UT. Click on the image to download.
SCO-116, a novel small-molecule NRF2 activator, potently induces NQO1 in multiple monkey ocular tissues, including retina, after topical ocular administration
Keith W. Ward, Dave Flory, W. Brooks Gentry, Ralph Henry, Misty Stevens
ARVO 2024
Kuria presented three posters at ARVO 2024 in Seattle, WA. Click on the images to download.
SCO-116 exhibits potent, selective activation of NRF2 suitable for use in treatment of ocular diseases
Ralph Henry, Dave Flory, W. Brooks Gentry, Yuko Katayama, Ryokichi Koyama, Shigemitsu Matsumoto, Yasuke Moritoh, Misty Stevens, Masanori Watanabe, Keith W. Ward
SCO-116, a novel small-molecule NRF2 activator, potently induces NQO1 in multiple rabbit ocular tissues
Misty Stevens, W. Brooks Gentry, Dave Flory, Ralph Henry, Brett Schneider, Keith W. Ward
SCO-116 protects retinal pigment epithelium from oxidative insult in vitro and preserves visual function and retinal structure in sodium iodate-induced geographic atrophy in rats in vivo
Keith W. Ward, Rafal Farjo, Dave Flory, W. Brooks Gentry, Ralph Henry, Didier J. Nuno, Misty Stevens, Phillip Vanlandingham
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